The Senate easily passed the fiscal 2017 defense authorization bill 85-13 on Tuesday after another skirmish on the floor blocked most amendments from gaining votes.Action stalled because senators who were unable to secure votes for their favored amendments blocked the chamber from considering other proposals. Armed Services Chairman John McCain (R-Ariz.) criticized his colleagues ahead of the vote, suggesting some were taking a “their way or the highway” approach.“As happy as I am about the size of the vote, we left out some very important amendments,” McCain said, reported the Hill. “When we take up a bill of this significance, not every senator can have his or her way.”Lawmakers adopted one amendment Tuesday permitting DOD to use Russian-made rocket engines to lift military and intelligence satellites into space through 2022.With the $602 billion measure cleared by the Senate, the two chambers will begin talks to reconcile their competing versions immediately, McCain said. He would not commit to reaching a deal on a conference report before Congress adjourns for a lengthy recess in July, but said that would be the goal.The annual defense policy bill will need to overcome a number of hurdles before becoming law, according to the story. The Office of Management and Budget has threatened to veto the two versions over a variety of provisions, including language eliminating the undersecretary of defense for acquisition, technology and logistics; limits on the size of the National Security Council staff; restrictions on the transfer of detainees from Guantánamo; language rejecting the administration’s request for a BRAC round in 2019; and a move allocating $18 billion from the overseas contingency operations account to the base budget. Dan Cohen AUTHOR
WILMINGTON, MA — Here are the obituaries published on Wilmington Apple during the week of November 18, 2018:Lived In Wilmington At Time Of Passing:Thomas H. Deechan, Jr., 71Louise (Nardo) Russo, 87Previously Lived In Wilmington:Thomas Joseph Donahue, 75Michael O’Brien, 62Worked In/Volunteered In/Connected To Wilmington:NoneLike Wilmington Apple on Facebook. Follow Wilmington Apple on Twitter. Follow Wilmington Apple on Instagram. Subscribe to Wilmington Apple’s daily email newsletter HERE. Got a comment, question, photo, press release, or news tip? Email email@example.com.Share this:TwitterFacebookLike this:Like Loading… RelatedWilmington OBITUARIES (Week of August 18, 2019)In “Obituaries”Wilmington OBITUARIES (Week of July 7, 2019)In “Obituaries”Wilmington OBITUARIES (Week of August 11, 2019)In “Obituaries”
(Phys.org) —The cytoskeletal proteins of eukaryotes polymerize into self-organized patterns even as pure solutions. However, to see more complex dynamics, like filament sliding or rotation, various motor proteins and cofactors usually need to be added to the solution. The ancestral bacterial proteins of actin and tubulin, namely FtsA and FtsZ, play a key role in bacterial cell division through the formation of a cytoskeletal structure known as the “Z” ring. Researchers Martin Loose and Tim Mitchison have studied these bacterial proteins in solution, along with bits of reconstituted membrane, and found that they support complex dynamics in the absence of any motor proteins. In their recent paper in Nature Cell Biology, they describe how these behaviors can spontaneously emerge. Cytoskeletal Ring Formation. Credit: labs.cellbio.duke.edu More information: The bacterial cell division proteins FtsA and FtsZ self-organize into dynamic cytoskeletal patterns, Nature Cell Biology (2013) DOI: 10.1038/ncb2885AbstractBacterial cytokinesis is commonly initiated by the Z-ring, a cytoskeletal structure that assembles at the site of division. Its primary component is FtsZ, a tubulin superfamily GTPase, which is recruited to the membrane by the actin-related protein FtsA. Both proteins are required for the formation of the Z-ring, but if and how they influence each other’s assembly dynamics is not known. Here, we reconstituted FtsA-dependent recruitment of FtsZ polymers to supported membranes, where both proteins self-organize into complex patterns, such as fast-moving filament bundles and chirally rotating rings. Using fluorescence microscopy and biochemical perturbations, we found that these large-scale rearrangements of FtsZ emerge from its polymerization dynamics and a dual, antagonistic role of FtsA: recruitment of FtsZ filaments to the membrane and negative regulation of FtsZ organization. Our findings provide a model for the initial steps of bacterial cell division and illustrate how dynamic polymers can self-organize into large-scale structures. Citation: The dynamic cytoskeleton in bacterial cell division (2013, December 10) retrieved 18 August 2019 from https://phys.org/news/2013-12-dynamic-cytoskeleton-bacterial-cell-division.html Explore further This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. The researchers studied a lipid bilayer preparation in which FtsA protein was readily attached through a special helix found at its carboxy terminus. When GTP was added, they found that the FtsZ was recruited to the membrane region, and was rapidly polymerized. After a critical density was reached, motile streams were seen moving in a single predominate direction, with complex rotating vortices found between them. The structures would persist for tens of minutes and rotated at speed of up to 11 degrees per second. While their system did not have all the components normally found in bacterial cells, the researchers noted that the vortices were reminiscent of the helical patterns seen during Z-ring assembly in E.coli and Bacillus subtilis. The formation of the patterns required the addition of ATP. The researchers found that no ATPase activity was present, and subsitution with ADP worked just as well. On the other hand, GTP was found to be hydrolyzed in the process, and only static filament bundles were formed when it was prevented.The researchers observed that the swirls had a preferred directionality. They explained this chirality as a result of polar molecules attaching to a single face of the bilayer, combined with the effects of bundling and treadmilling in curved FtsZ filaments. They also note that the attachment of enzymes to the Z-ring could occur in a spatially organized fashion with the predominate force for inward growth in cell division arising from bond formation during cell wall biosynthesis.The larger question of asymmetry in cells often escapes everyday notice. Neurons, in particular, are highly polarized with the axon defining a principle direction. Yet very little in terms of neuronal function has been ascribed to any particular handedness. As mentioned previously, one issue which might be further explored in this vein would be orientation specific effects felt beyond the immediate cell, like the direction of glial wrapping, for example. Other possible effects like rotation of free microtubules as a result of the directed transport of various cargo have scarcely been studied, but could have interesting implications for the organization of cells. Simulation, like one recent model exploring the role of the GTP cap region in microtubule dynamics, will be an important compliment to these kinds of in-vitro experiments. The study of the intrinsic pattern formation capability of more primitive cytoskeletal proteins will lead to greater understanding of the functions of their diverse, and uniquely optimized descendants found today in eukaryotic cells. Journal information: Nature Cell Biology Scientists deconstruct process of bacterial division © 2013 Phys.org
Monday, March 4, 2019 Share Travelweek Group << Previous PostNext Post >> Tags: Bahamas, Nassau, Travel Advisories “Safety of visitors is of paramount importance”: The Bahamas responds to U.S. travel advisory NASSAU — The Ministry of Tourism & Aviation for The Bahamas has responded to a travel advisory issued by the United States following a recent spate of crime.The Ministry notes that the advisory remains at a Level Two, recommending caution but not actually urging visitors to delay or cancel their travel plans to the islands.“We recommend that travellers to any destination maintain awareness of their surroundings and exercise basic precautions, as they likely would in their home cities and when not on holiday,” said the Ministry in a statement.The statement also notes that the vast majority of the country’s six million annual visitors stay on the island without any incident. According to the Royal Bahamas Police data for 2018, there were only 43 incidents involving tourists, of which 30 involved U.S. nationals and nearly all were minor offences.The Ministry of Tourism applauds the efforts made by law enforcement, which significantly reduced serious crimes like murder (-25%), armed robber (-18%), attempted robber (-19%) and shoplifting (-23%).More news: Honolulu authorities investigate arsons at 3 Waikiki hotels; no injuries reported“The safety of residents and visitors is of paramount importance,” said the Ministry. “Efforts to maintain and improve security are a constant priority for Bahamas authorities as is true for all governments.”Safety and security efforts include the use of CCTV in addition to a heightened police presence with foot, bicycle and motor patrols across all areas referenced in the advisory and tourist areas. Additional Beach Enforcement Officers have also been deployed to beaches, and regular communication is in effect between the Royal Bahamas Police Force Land and Marine Units, Royal Bahamas Defence Force Harbour Patrol Unit, and the Ministry of Tourism to ensure concerns are addressed quickly.The U.S. Travel Advisory for The Bahamas was issued on Feb. 25 in response to “violent crime, such as burglaries, armed robberies, and sexual assault,” which the U.S. government said is common, “even during the day and in tourist areas.” The advisory also noted that the vast majority of crime occurs on New Providence and Grand Bahama islands, activities involving commercial recreational watercraft – including water tours – are not consistently regulated, and that “jet-ski operators have been known to commit sexual assaults against tourists.”More news: GLP Worldwide introduces first-ever Wellness programsThe advisory goes on to encourage travellers to “exercise caution in the area known as ‘Over the Hill’ (south of Shirley Street) and the Fish Fry at Arawak Cay in Nassau, especially at night.” Posted by
By WVUA 23 Student Reporter Sam LutherTemporary Emergency Services in Tuscaloosa is giving out blankets and heaters to help kick off the new year, and it’s all for free.All you have to do is show up to the TES building at 1705 15th St. in Tuscaloosa and show employees your photo ID. The only catch? You can’t have received a heater in the past two years.Space heaters can cost anywhere from $20 to hundreds, so why give them away for free?Shannon Morgan with TES said there’s a simple reason.“We don’t want people to freeze,” she said. “And there are many of our clients who have gone all summer long without their gas being on. They don’t have sufficient heat in their homes.”If you’d like to help TES provide blankets or heaters to the needy, you can drop off space heaters or blankets at TES during normal business hours or donate online at temporaryemergencyservices.org.
ADE Gardner has joined Keiron Cunningham’s backroom staff as Assistant Strength and Conditioning Coach.He will work with Head of Strength and Conditioning Matt Daniels for the 2015 season as the Champions look to retain their Super League crown.It also means the former Barrow Border Raider has called time on his playing career after more than 350 appearances.Ade said: “Whilst it is difficult to walk away from the game in terms of playing, I’m delighted to take on this role at the club.“I was going to retire at the end of 2015 but the club offered me this role to move into and it made sense. In the end it was the best decision for me and my family.“I am retiring with a heavy heart. I had 15 good seasons at the best club in the world and have fond memories not only here but with Barrow, Hull KR and Great Britain too.“But the opportunity to remain at this great club was too good to turn down.“Strength and Conditioning has always been an area of the game I have a deep interest in. Over the years I have put in a lot of work both on and off the field and looked at the science of what we do as players to continue to perform at a high level.“I am currently in the third year of a Sports Science degree at Loughborough University and this role will enable me to gain good insight and experience into this part of the game.”He continued: “I have worked with Keiron for a number of years. We have a similar ethos and work ethic. The fact he wanted me to take on this role gives me a lot of confidence.“I’m looking forward to working with the players who have been part of this club’s success and taking that ethic and mentality to the younger players who are in the first team squad and coming through the system.“I’d never say never about playing again but the focus for now is on this new role and I can’t wait to get started.”Ade joined Saints in 2001 from Barrow and has become one of the most prolific wingers ever to play for the club.He scored 173 tries in 286 games for Saints and has been part of its most successful era.After establishing himself as a first team regular in 2003, he was the Club’s highest try scorer in the 2006, 2007 and 2008 Super League seasons.Gardner was integral to the club’s 2006 Grand Slam and scored two vital tries in the win over Brisbane in the World Club Challenge in 2007.He also went on to play seven times for England and five times for Great Britain.Head Coach Cunningham added: “We’re delighted Ade has agreed to join the backroom staff here at the club.“He is a superb professional who will bring a wealth of knowledge to the role built up over several years as a top level rugby league player.“His work ethic is second to none and he has always been one of the best trainers at the club.“That will help us deliver what we want to achieve as it sets an example to the young players we have not only in the first team but throughout our academy structure too.“The fact he is in his third year studying Sports Science at University will also bring a great deal of knowledge and experience to the squad.”You can here an extended interview with Ade in the Fanzone or by subscribing to the Saints In Touch Podcast.