After spending some time with Mudcrutch earlier this year, beloved singer/songwriter Tom Petty has announced a major tour with the Heartbreakers. The beloved outfit has revealed 34 tour dates nationwide, spanning from April 20th through July 27th. The shows mark the band’s first full length tour since 2014, and will celebrate the group’s 40th anniversary.Tom Petty & The Heartbreakers will start their tour in Oklahoma City, ultimately heading through the South to venues like Red Rocks Amphitheatre, ultimately traveling through the Midwest and into the Northeast. They’ll end the run with two nights at the Forest Hills Stadium in New York, NY.Tickets for the new tour will go on sale next Friday, December 16th, but there are fan club pre-sale options available. All of those details can be found on Petty’s website. A full list of tour dates is printed below.Tom Petty & The Heartbreakers 40th Anniversary TourApril 20 /// Chesapeake Energy Center /// Oklahoma City, OK*April 22 /// American Airlines Arena /// Dallas, TX*April 23 /// Verizon Wireless Arena /// Little Rock, AR*April 25 /// Bridgestone Arena /// Nashville, TN*April 27 /// Philips Arena /// Atlanta, GA*April 29 /// Cynthia Woods Mitchell Pavilion /// Houston, TX*May 2 /// Frank Erwin Center /// Austin, TXMay 5 /// Perfect Vodka Amphitheatre /// West Palm Beach, FL*May 6 /// Amalie Arena /// Tampa, FL*May 8 /// FedEx Forum /// Memphis, TN*May 10 /// StateFarm Center /// Champaign, IL*May 12 /// Scottrade Center /// St. Louis, MO*May 13 /// Klipsch Music Center /// Indianapolis, IN*May 29-30 /// Red Rocks Amphitheatre /// Morrison, CO June 2 /// Sprint Center /// Kansas City, MO*June 3 /// Xcel Energy Center /// St. Paul, MN*June 5 /// Wells Fargo Arena /// Des Moines, IA*June 7 /// Schottenstein Center /// Columbus, OH*June 9 /// PPG Paints Arena /// Pittsburgh, PA*June 10 /// Quicken Loans Arena /// Cleveland, OH*June 12 /// US Bank Arena /// Cincinnati, OH*June 14 /// XFINITY Theatre /// Hartford, CT*June 16 /// Prudential Center /// Newark, NJ*June 17 /// Mountain Jam Festival /// Hunter, NYJune 29 /// Wrigley Field /// Chicago, IL† July 1 /// Wells Fargo Arena /// Philadelphia, PAJuly 2 /// CMAC Performing Arts Center /// Canandaigua, NY July 5-6 /// Marcus Amphitheater-Summerfest /// Milwaukee, WI† July 15 /// Air Canada Centre /// Toronto, ONTJuly 18 /// DTE Energy Music Theatre /// Detroit, MIJuly 20 /// TD Garden /// Boston, MAJuly 23 /// Royal Farms Arena /// Baltimore, MDJuly 26-27 /// Forest Hills Stadium /// Queens, NY‡*with very special guest Joe Walsh†with very special guest Chris Stapleton‡on-sale January 14
The paper intriguingly suggests that much more is to be learned. Ongoing studies will further elucidate this new, long-range chromatin-based mechanism of developmental gene regulation. The developmental regulation of cohesin loop extrusion processivity will likely be an important mechanism by which other large genetic loci harness biological activities over long chromosomal distances.The findings also provide further insights into how cohesin-mediated loop extrusion can contribute to mechanisms of oncogenic genomic translocations/deletions in early B and T lymphocyte cancers. These and related earlier findings have provided a basis for the Alt lab to generate novel humanized mouse models for HIV1-Vaccine testing and for broadening the activity, or discovery, of novel therapeutic antibodies. Researchers in the laboratory of Frederick Alt of the Howard Hughes Medical Institute and Program in Cellular and Molecular Medicine (PCMM) at Children’s Hospital Boston made a groundbreaking discovery at the nexus of chromatin biology and immunology. Their work, recently published in Nature, showed that physiological deregulation of the WAPL chromatin-maintenance factor allows developing B lymphocytes to scan linearly through very long chromosomal loops to find and join gene segments that form diverse antibody repertoires.Recently the Alt group discovered that V(D)J recombination and IgH class switch recombination (CSR), two discrete mechanisms of programmed genetic rearrangement in lymphocytes, both critical for adaptive immunity, are mechanistically driven by a basic process associated with management of the architecture of chromosomal genomes: chromatin loop extrusion (“Chromatin loops unlock antibody class switching”).The implications of this research are potentially relevant to mechanisms of immunodeficiency and auto-immunity due to the impact of this mechanism on generating antibody diversity, as indicated by effects of mutations of cohesin complex factors being related to such diseases. Read Full Story
“Some planes are flying with less than 10 passengers, but we feel we need to keep that transport infrastructure,” the person added.An official at the Japan Civil Aviation Bureau, which oversees the carriers, described it as “business as usual”, with the airlines setting schedules based on business conditions. The government only requires them to offer refunds or new bookings to passengers affected by cancellations, he said.Neither carrier is government owned, but ties with regulators are close, with officials and politicians willing to extend financial help in troubled times to support a domestic aviation network that connects an island archipelago stretching almost 3,000 kilometers. In a stimulus package equivalent to a fifth of Japan’s annual GDP, Prime Minister Shinzo Abe’s government has promised financial support for the carriers, although it has yet to say how much.The Scheduled Airlines Association of Japan, which represents ANA, JAL and 17 others, estimates that the pandemic will cost its members some 500 billion yen ($4.64 billion) in lost revenue by the end of May.Over a year that deficit could balloon to 2 trillion yen, the industry lobby group predicts.ANA has asked commercial lenders and the state-run Development Bank of Japan for 400 billion yen in aid, as it burns through cash during the crisis.”If the coronavirus downturn lasts a year ANA will need at least 1.3 trillion yen,” said a second airline industry source familiar with the matter, asking not to be identified. JAL said on Friday it would operate at 40% of capacity on domestic routes until the end of the month, with ANA reducing it to 49%.The decision to keep many aircraft flying is set to add further financial strain on the Japanese carriers. Their peers in India, Thailand and the Philippines have grounded all domestic flights under government orders, while those in Australia and New Zealand are flying less than 5% of their normal schedules due to travel restrictions and reduced demand.Japan has not restricted domestic travel, and authorities are only requesting people to stay in and asking bars and restaurants to temporarily close without penalty.”The government has declared an emergency, but hasn’t asked the airlines to reduce flights, rather they want to maintain the transport infrastructure,” said a person familiar with operations at the airlines, who was not authorized to talk to media. Topics : Japan’s top airlines are operating at nearly half their domestic capacity even though the coronavirus outbreak has left seats on flights mostly empty, amid a lack of clear government directives on the functioning of transport infrastructure in the crisis.ANA Holdings Inc and Japan Airlines Co Ltd (JAL) , Japan’s two biggest airlines, have cut around 90% of international flights but left much of their domestic network intact, industry data showed. The two normally fly around 800 or more domestic flights daily.Until announcing fresh cuts on Friday the airlines were flying at around two-thirds of capacity in Japan with 10% of the usual demand, according to the airlines. That is despite the government declaring a one-month state of emergency in major cities on April 7 which was expanded on Thursday to include the entire country.
RelatedPosts COVID-19: NCAA to revoke erring airlines licence over non-compliance FRSC to Schools: We’ll arrest, prosecute drivers who flout COVID-19 rules Sanwo-Olu: We’re committed to fulfilling promises to Lagosians The Confederation of African Football has released guidelines for return of football activities on the continent after it was brought to a halt following the spread of COVID-19 pandemic.The continental body said this in a statement on its website on Monday. It stated that series of meetings has been held regarding the future of competitions, stressing that the CAF Medical Committee in collaboration with the Technical and Development Department and a team of experts has put together a comprehensive plan to guide the Member Associations on the restart of football activities on the continent.The 27-page document, titled: “CAF Guidelines to Resume Football in Africa,” emphasized on the health of the major stakeholders (Players, Officials, Fans, Partners) as the essential element, which should constitute the basis of all decisions regarding the reintroduction of football activities across the continent supported by the authorisation of relevant State Authorities.The plan also highlighted on effective and continuous medical assessment (testing) of players and officials, guidelines for training sessions, disinfection of sporting facilities, as well as strict adherence to the global preventive protocols.CAF Acting General Secretary Abdelmounaim Bah said: “This comprehensive document is major step towards resuming football on the continent. Based on recent developments, it is important we have a plan in place to guide our stakeholders on the return of continental and domestic competitions, and the need for an all hands on deck approach.“Many considerations were factored into the putting together of the document by our team of experts notably the specificities of the continent. Together with strategies established by local authorities, it provides the MA’s with adequate information to resume operations upon receiving the green light.” Meanwhile, the Organising Committee for Interclubs Competitions and Management of Club Licensing, and the Organising Committee for Women’s Football held meetings via video-conference last week on the future on the various competitions.The CAF Executive Committee, scheduled to meet on June 30, 2020 via video-conference, will make pronouncements on the recommendations by the respective Standing Committees. Details of the Executive Committee meeting to be announced in due course.Some of the competitions that were suspended included Champions League, CAF Confederation Cup, Women Afcon 2020 qualifier, Tokyo 2020 Olympic Games, Intercontinental qualifying match for Tokyo 202 Olympic Games and FIFA 2022 World Cup qualifiers.Tags: cafCAF Medical CommitteeCOVID-19
It was something of a surprise, therefore, to see the 24-year-old play down the injury on Twitter the day after the derby. “Gracias a todos por los mensajes. Gracias a dios fue solo un mal momento/ thank you all for your messages. thank god it was nothing,” Rojo wrote. United believe Rojo, who speaks only limited English as he has only been in the country for just over two months, made something of a mistake in his translation of the Spanish part of his tweet. “Solo un mal momento” translates as “only a bad moment”, rather than “nothing”, and the club believe the defender’s injury is serious. Rojo was discharged from hospital on Sunday evening and the club confirmed that the defender had suffered a dislocation. Medical estimates of a recovery time from such an injury range from six weeks to three months. In 2011 United defender Rafael was out for three-and-a-half months with a dislocated shoulder. Although Rojo is yet to convince many he is the answer to United’s defensive problems, his absence is a blow to Louis van Gaal. Manchester United expect to be without Marcos Rojo for some time despite the defender’s claim his shoulder injury is not serious. The Argentinian was carried off on a stretcher in the second half of United’s 1-0 derby defeat to City at the Etihad Stadium on Sunday after he mis-judged a sliding tackle and dislocated his left shoulder. The versatile defender seemed to be in some pain when he was carried off after receiving around two minutes’ worth of treatment. The United manager is set to be without Phil Jones for some time as the England centre-back is suffering from shin splints – his second injury of the season. Jonny Evans has not played for over six weeks because of an ankle injury while Chris Smalling will serve a one-match ban for his careless dismissal against City. That means Van Gaal is likely to field Michael Carrick as a makeshift centre-half alongside either Tyler Blackett or Paddy McNair for Saturday’s Barclays Premier League game against Crystal Palace. One thing in Van Gaal’s favour is that behind his makeshift back four he will be able to field arguably the most in-form goalkeeper in the top flight. David de Gea pulled off some stunning saves to deny Everton last month and he once again proved his worth against City, who could have scored many more had it not been for the Spanish stopper. De Gea has been very pleased with his recent performances, but he would prefer it if United were winning as well. “My form is very good. I am playing the best football of my career and I want it to continue, but the most important thing is that we all play well as a team,” De Gea told Press Association Sport after the derby defeat. “The next match is at home and we will train hard all this week to make sure we get all three points.” Van Gaal will not have enjoyed looking at the Premier League table on Sunday night, when United dropped to 10th. Despite a huge amount of enthusiasm and self-confidence, the fact remains that Van Gaal has endured a worse start to his reign than David Moyes, who was sacked after 10 months last season. But Wayne Rooney retains supreme faith in the man who appointed him United captain in the summer. Rooney told MUTV: “We’re working on different things, which a lot of us haven’t been used to. We’re certainly heading in the right direction. “We’re progressing each week and playing some nice football. We need to turn that into results and I’m sure we can do that if we keep working, keep learning and keep doing what the manager wants from us.” Rooney also said Smalling would bounce back from his two careless cautions, which effectively cost United the match. “Chris is disappointed,” the England skipper said. “It’s tough when you get sent off, especially in a derby and with such a long time to go in the game it made it difficult for the rest of us to hold on. “I’m sure Chris will learn from that.” Press Association
As students flocked to the University Park Campus for the first day of classes Monday, new, portable bike lanes flanking Trousdale Parkway prompted varied reactions from students.Traffic control · Students tested out the new bike lanes on Trousdale Parkway on the first day of classes for the fall semester Monday. According to Student Affairs, the lanes are meant to reduce collisions. – Ani Kolangian | Daily Trojan Part of a joint project by USC Student Affairs and Undergraduate Student Government, the bike lanes are intended to enable students to bike up and down Trousdale without interfering with pedestrian traffic.An email sent to students by Student Affairs mentions that the new bike lanes are the result of the “We are Considerate. We Are USC.” campaign started in 2011.“The goal is to make the campus more hospitable to bikers and to benefit the students on campus,” said Michael Jackson, vice president of student affairs.If these lanes prove successful, USC hopes to expand the bike lanes to thoroughfares, such as Childs and Watt ways.“Student Affairs is excited about the new bike lanes and hopes this new experiment will be the first step in a broader solution to help keep USC a bicycle and pedestrian friendly campus,” said Tom Studdert, director at USC Orientation Programs. “This goes a long way in helping us maintain safety for all Trojans, particularly in the center of campus.”USG President Mikey Geragos said USG became interested in bike lanes because of campus safety.“The issue of bike safety on campus came to my attention this summer,” Geragos said. “While the bike lanes are by no means the only solution to this issue on campus, we hope that they work.”For bikers around the university, these bike lanes provide a much-needed departure from Trousdale before its makeover this summer.“Biking on Trousdale, especially when school starts, is really tough and kind of crazy,” Adrian Pedroza, a sophomore majoring in psychology. “I’ve even seen head-on collisions.”A survey conducted by bikeusc.org, a campus cycling information group, gave a factual basis for the new bike lanes. The study reported that nearly 25 percent of USC’s undergraduate student body has had a collision with a bike in the past year.The same survey also showed 20 percent of undergraduate students had no regular cycling experience prior to biking on campus, suggesting pedestrian unfamiliarity with bicycles, coupled with rider inexperience, often results in the frequent collisions on campus.Last week, Dept. of Public Safety officers placed large portable metal dividers on Trousdale and urged pedestrians to stay out of bike lanes.Several days after first sightings of the dividers, construction crews painted permanent bike icons on the sides of Trousdale. These sharrows, or shared-lane markings, coupled with the metal dividers, are intended to decrease the risk factor in having bicyclists and pedestrians share walkways.In the past, campus cyclists like Pedroza found themselves in the way of pedestrians; they were also forbidden to ride on Trousdale during peak hours. Though Student Affairs said the peak hours rule and other safety precautions are still in effect, many confused travelers have needed DPS officers to inform about the new lanes and how to use them.“It might take a little while for people to get used to using the bike lanes, but overall, it should help promote pedestrian safety,” said Selena Ng, a freshman majoring in business administration.Though the project is in its preliminary stages of development, — evident by the placement of the bike lanes on only one campus walkway — Student Affairs hopes that the lanes will foster a more orderly and safer environment for pedestrians and cyclists.Nicole Poritzky, an undeclared freshman, said the lanes made walking to class during peak hours easier for pedestrians.“It’s a good idea and makes for safer travelling,” Poritzky said. “Now that I see how busy [Trousdale] can be at rush hour, I’m really glad there’s a system in place.”Not all, however, are so optimistic. Matthew Lopez, a sophomore majoring in history, likes the lanes but thinks they could be marked better.“I’m an aimless walker, so I like that it keeps me from wandering into bikers’ paths,” Lopez said. “I do think that the lane [boundaries] could be more clear, because a lot of people seemed confused.”
13 Right-back: Jonjoe Kenny (Everton) – Part of the Under-17 European Championship-winning squad of 2014, along with Woodman, Dominic Solanke and captain Lewis Cook. Kenny impressed in South Korea and is highly thought of at Goodison Park. He did well during a loan spell at Oxford last season and is expected to add to his two first-team appearances during the forthcoming 2017-18 campaign. Goalkeeper: Freddie Woodman (Newcastle United) – Has represented his country at all levels from under-16 up to under-21. His second-half penalty save in the final proved crucial. Yet to feature in a match for Newcastle, having been loaned out to Hartlepool, Crawley and Kilmarnock. Was awarded the Golden Glove, given to the best goalkeeper of the tournament. 13 13 Midfield: Lewis Cook (AFC Bournemouth) – Has represented his country at all levels from under-16 to under-20 and on Sunday joined Bobby Moore as the only other England captain to lift a FIFA World Cup. Cook, who scored in the group stage against Guinea, signed for Bournemouth from Leeds for £6million last summer and made a handful of Premier League appearance for the Cherries last season. 13 13 Left-back: Kyle Walker-Peters (Tottenham) – Has also represented England at under-18 and under-19 level and is highly regarded at Spurs, where he signed a new three-year contract in February. He was outstanding in the semi-finals against Italy when asked to play at left-back, rather than in his more familiar position on the right-hand side of the defence. 13 13 13 Midfield: Dominic Solanke (Liverpool) – Due to join Liverpool from Chelsea on July 1, Solanke scored four times in South Korea and was awarded the Golden Ball given to the player of the tournament. Previous winners of the accolade include Diego Maradona, Lionel Messi, Luis Figo, Paul Pogba and Sergio Aguero. Has represented England at all levels from under-16 to under-21. Had a decent loan spell in Holland with Vitesse in the 2015-16 season. 13 Midfield: Joshua Onomah (Tottenham) – Saw a 30-yard effort strike the crossbar and bounce down on the line during the second half of the final. Has been solid in a deeper midfield role for England during the competition, despite often appearing for Spurs in a more advanced role in cameos under boss Mauricio Pochettino. Has represented England at every level except for the senior side. Midfield: Kieran Dowell (Everton) – Capped by England at under-16 to under-20 level. He scored the winning goal in the 1-0 victory against hosts South Korea in the group stages. He made his Everton debut back in 2014 in the Europa League and made his Premier League bow for the club in April 2016. Midfield: Ademola Lookman (Everton) – Scored three times during the tournament, including in the semi-finals against Italy. Everton won the race to sign the youngster from Charlton in January, paying a reported £7.5million. He enjoyed a dream debut with a goal in a 4-0 win over Manchester City at Goodison Park but was used sparingly by Blues boss Ronald Koeman towards the end of last season. 13 Centre-back: Jake Clarke-Salter (Chelsea) – Also capped at under-18 and under-19 level for England. His clash of knees with Adalberto Penaranda resulted in Venezuela being awarded the penalty which Woodman saved. He had a loan spell at Bristol Rovers last season and it has been reported that he has been earmarked by the Chelsea academy staff as having the potential to replace the departing John Terry. Centre-back: Fikayo Tomori (Chelsea) – Tomori scored an own goal in the draw against Guinea but showed good character to go on and have a solid tournament thereafter. The Canada-born defender made his Chelsea debut as a substitute in the final game of the 2015-16 season against Leicester at Stamford Bridge. He spent the second half of last season on loan at Brighton as Chris Hughton’s team secured promotion to the Premier League. 13 13 Forward: Dominic Calvert-Lewin (Everton) – Wrote his name into history by scoring the winning goal in the final. He also scored in the win over Argentina in the group phase. He joined Everton from Sheffield United last summer and made his Toffees debut against Arsenal in December before scoring his first goal for the club against Hull in March. 13 SUB: Ainsley Maitland-Niles (Arsenal) – Introduced from the bench after 71 minutes for Lookman. He made his debut for Arsenal at the age of 17 in a Champions League clash with Galatasaray. The teenager had a loan spell at Ipswich in 2015 but his progression at the Emirates has stalled somewhat. Dominic Calvert-Lewin and Freddie Woodman grabbed the headlines in a team of heroes as England won the Under-20 World Cup by beating Venezuela in South Korea.Paul Simpson’s Young Lions were the first England side to reach a world showpiece for over half a century and they followed in the footsteps of Sir Alf Ramsey’s team, who lifted the Jules Rimet Trophy in 1966.Everton’s Calvert-Lewin scored the game’s only goal after 35 minutes while a second-half penalty save from Newcastle goalkeeper Woodman preserved England’s 1-0 lead and ensured they became world champions.But who are these young heroes? And are they going to be the next big thing?Click the right arrow, above, to see the background of the players who featured in the final in South Korea and helped England become world champions. SUB: Sheyi Ojo (Liverpool) – Came on as a substitute for Dowell after 62 minutes. Liverpool snapped up the winger from MK Dons in 2011 and has made a handful of first-team appearances for the Reds, as well as spending time out on loan at Wigan and Wolves. Has represented his country at all levels from under-16 to under-20.